NSC 16640. Find pure quality glutaric acid anhydride that retain acidic properties and serve purposes optimally at Alibaba.com. Glutaric anhydride, 95%. Nuestros distribuidores registrados le ayudarán a obtener toda la información necesaria y las especificaciones del producto. Glutaric acid may be used for the following studies: • Complexation with DL-lysine. Additional applications such as the production of polymers, corrosion inhibitors, surfactants and metal finishing compounds might be available. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. Other . Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. Mol. Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. Anhydrid kyseliny glutarove. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. It has a role as a human metabolite and a Daphnia magna metabolite. Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. Glutaric anhydride. The Prior Informed Consent Regulation administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. Lazrek HB, Vasseur JJ, Secrist J 3rd, Engels JW Nucleosides Nucleotides Nucleic Acids 2007;26(8-9):1103-6. doi: 10.1080/15257770701519452. Molecular Weight 114.10 . A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. EC Inventory, FCM and Articles Regulation, Annex I - Authorised Substances . Pharmaceutics 2015, 12 (7), 2505-2516. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Union List of Authorized Substances: Annex I, Plastics Food Contact Regulation 10/2011/EU, as amended by Regulation 2020/1245/EU, 3 September 2020, Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, Plastic Materials and Articles Regulation, EC Inventory, FCM and Articles Regulation, Annex I - Authorised Substances, Other, FCM and Articles Regulation, Annex I - Authorised Substances, Pre-Registration process, FCM and Articles Regulation, Annex I - Authorised Substances, 5-[(4-carboxybutanoyl)oxy]-5-oxopentanoic acid, EC Inventory, C&L Inventory, Registration dossier, Pre-Registration process, Other, FCM and Articles Regulation, Annex I - Authorised Substances, Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). With the dehydrating agent, such asacetic anhydride, heating the glutaric acid to dehydrate it and obtain glutaric anhydride(108-55-4). Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) EC Number 203-593-6. Occupational exposure limit (OEL) values are derived within two legal frameworks that form an integral part of the EU’s mechanism for protecting the health of workers. Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. Welcome to the ECHA website. Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. IF ON SKIN: Wash with plenty of soap and water. Heating mixture of binary carboxylic acid (succinic acid, glutaric acid, adipic acid) to dehydrate succinic acid and glutaric acid, then take some of the distillate under a certain temperature to get glutaric anhydride(108-55-4) . InfoCards are generated automatically based on the data available at the time of generation. the products in which the substance may be used) may refer to uses as intermediate and under controlled conditions, for which there is no consumer exposure. More information about CAS and the CAS registry can be found here. Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. The source of the information is mentioned in the introductory sentence of the hazard statements. What is the Classification and Labelling Inventory? Search results for L Glutamic Acid at Sigma-Aldrich. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. Release to the environment of this substance can occur from industrial use: manufacturing of the substance. Causes serious eye damage. Nitinol™ Nickel Titanium Shape Memory Alloys, Specpure® Inorganic Standards for Water Analysis, Specpure® Oil-Based Standards for Wear Metal Analysis, Specpure® XRF Standards for Petroleum Products, Cellular Growth & Attachment Factors - BT Products, POCO Electron Beam Crucibles & Hearth Shields (Carbon Graphite), Boron, Phosphorus, Silicon, and Sulfur Compounds, Sugars, Steroids, Amino Acids, and Nucleotides, Precious Metal Compounds - Homogeneous Catalysts. The per substance REACH registration status is being calculated and will be made available as soon as possible. … Compare Products: Select up to 4 products. More information about Classification and Labelling is available in the Regulations section of ECHA website. The result was verified by NMR spectroscopic experiments, which moreover showed that βCD … (M-F, 8AM-5PM EST) Search results for glutamic anhydride at Sigma-Aldrich. Pentanedioic anhydride. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). With the increase of glutaric anhydride content, the total heat released during the curing reaction and the glass transition temperature (Tg) increased. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Harmful if swallowed. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. Glutaric acid is an alpha,omega-dicarboxylic acid that is a linear five- carbon dicarboxylic acid. t. test method (at the 99% confidence limit) was used for determining MDL, where the standard deviation (SD) of the peak area of seven injections is multiplied by 3.71 Molecular Formula C 5 H 6 O 3; Average mass 114.099 Da; Monoisotopic mass 114.031693 Da; ChemSpider ID 7652 These notifications can be provided by manufacturers, importers and downstream users. Glutaric acid anhydride. Their reactions with bases, called "neutralizations", are accompanied by … Carbon-13 nuclear magnetic resonance spectra of some mono- and di-alkyl substituted glutaric anhydrides *Please select more than one item to compare Clear. Wear protective gloves/protective clothing/eye protection/face protection. More information about the EC Inventory can be found here. Take off contaminated clothing and wash before reuse. Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): Also referred to as the Plastics Implementation Measure (PIM), this Regulation provides the Union List of monomers and other substances authorized in the manufacture of food contact plastics. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). BRN 0110051. dihydro-3H-pyran-2,6-dione. email: ecommerce@alfa.com, Specialty/Bulk Sales Tel: 1-888-343-8025 or 1-978-521-6401 Get medical attention. P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c-X, Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the. Substances listed in the EINECS, ELINCS, or NLP inventories. H302-H312-H315-H318. Glutaric acid anhydride . …atoms, behaves similarly to yield glutaric anhydride. Precautionary Statements: Crystallization of glutaric anhydride in the presence of β-cyclodextrin (βCD) from aqueous solution resulted in crystals of the glutaric acid/βCD inclusion complex. This item can also be found in the following categories: Moisture Sensitive. REACH registered substance data was upgraded on 9th November. (M-F, 8AM-5PM EST) Use only outdoors or in a well-ventilated area. Complexes have been reported to possess zwitterionic lysinium ions (positively charged) and semi-glutarate ions (negatively charged). It is also used in the production of polymers, particularly modified unsaturated linear (epoxy) polyesters and as a raw material in the manufacture of flavors. Moisture sensitive. By browsing our website without changing the browser settings you grant us permission to store that information on your device. It is the responsibility of the substance manufacturers and importers to consult official publications, e.g. Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. GLUTARIC ACID is a carboxylic acid. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. Privacy Policy The POPs Regulation bans or severely restricts the production and use of persistent organic pollutants in the European Union. 3 Temperatures as high as 200 °C have Glutaric acid may be employed as starting reagent in the synthesis of glutaric anhydride. Keep, Replace your shopping cart with these items? c + 139.0 0.9980 0.06 Adipic acid A = 1787 . Their decomposition at temperatures above 300°C and a heating time as long as 6 h generates CO 2 and condensation products. The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). In that case, the ATP (Adaptation to Technical Progress) number is displayed. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. Anhydrid kyseliny glutarove [Czech] EINECS 203-593-6. InfoCards are updated when new information is available. Glutaric anhydride . Danger! ECHA has no public registered data on the types of manufacture using this substance. Succinic acid anhydride and glutaric acid anhydride are relatively stable molecules. glutaric anhydride . or 1-978-521-6350 MDL number MFCD00006679. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. Wash off immediately with plenty of water for at least 15 minutes. With the increase of glutaric anhydride content, the total heat released during the curing reaction and the glass transition temperature (Tg) increased. Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. This substance has an industrial use resulting in manufacture of another substance (use of intermediates). I agree A glutaric acid ester as carrier system for sustained delivery of lamuvidine (3TC) dimers. Chen, H.; Liu, C.; Chen, D.; Madrid, K.; Peng, S.; Dong, X.; Zhang, M.; Gu, Y. Bacteria-Targeting Conjugates Based on Antimicrobial Peptide for Bacteria Diagnosis and Therapy. Fax: 1-800-322-4757 Glutaric anhydride is used in the production of glutaric acid family pharmaceuticals. First-aid measures General Advice If symptoms persist, call a physician. Process for manufacturing low-acid, glutaric-anhydride-containing copolymers Download PDF Info Publication number US4874824A. Information on precautionary measures and the safe use is submitted by the registrant of a substance and the registrant is solely responsible for its accuracy and completeness. According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed, causes serious eye damage and causes skin irritation. PubChem Substance ID 24895139. Adipic anhydride by pyrolysis around 240°C generates CO 2 and cyclopentanone, as shown in the following reaction: (14.4.3) Its derivatives are also used in certain corrosion inhibitors, some surfactants and metal finishing compounds. Incompatible withstrong oxidizing agents, acids, bases, alcohols and amines. © Copyright 2021 Alfa Aesar, Thermo Fisher Scientific. Substances may have impurities and additives that lead to different classifications. The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. Glutaric anhydride for synthesis. Clear, Add the items to your existing shopping cart? ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes. heptanoic anhydride glutaric acid, methyl ester Valeric acid methyl ester Valeric acid ethyl ester octanoic anhydride. This website uses cookies to ensure you get the best experience on our websites. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. Keep, Remove your current shopping cart and replace with the saved cart? We apologise for the inconvenience in the meantime. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. Ambient temperatures. Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates). REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. Hazard Statements: A wide variety of glutaric anhydride options are available to you, There are 2 suppliers who sells glutaric anhydride on Alibaba.com, mainly located in Asia. The examples provided are generic examples and may not apply to the specific substance you are viewing. disodium tetraborate EC no. Its derivatives are also used in certain corrosion inhibitors, some surfactants and metal finishing compounds. This substance is used for the manufacture of: chemicals. UNII-63OFI15S80. in case of consumer and professional uses). Glutaric anhydride 95% CAS Number 108-55-4. It is used as a raw material in the manufacture of flavours. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data. The EC or list number is the primary substance identifier used by ECHA. Structure, properties, spectra, suppliers and links for: Glutaric anhydride, 53715-97-2. IF IN EYES: Rinse cautiously with water for several minutes. Glutaric anhydride EC Number: 203-593-6 EC Name: Glutaric anhydride CAS Number: 108-55-4 Molecular formula: C5H6O3 IUPAC Name: 5-[(4-carboxybutanoyl)oxy]-5-oxopentanoic acid This information has not been reviewed or verified by ECHA, and may change without prior notice. Furthermore, some substances can be found in an article, but with unlikely exposure (e.g. NACRES NA.23 If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. Empirical Formula (Hill Notation) C 5 H 6 O 3. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. The EC Number is the numerical identifier for substances in the EC Inventory. All Rights Reserved. 80% adipic acid. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. Immediately call a POISON CENTER or doctor/physician. L-Glutamic acid (1) is an inexpensive and readily available amino acid.If it is heated between 160-180 °C, usually for a few hours, a cyclization reaction occurs to give 5-oxoproline (pyroglutamic acid, 2) in good yield. For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet. Glutaric anhydride . c + 145.9 0.9985 0.04 *The single-sided Student’s . 257 glutaric anhydride products are offered for sale by suppliers on Alibaba.com, of which pharmaceutical intermediates accounts for 1%. Continue rinsing. Glutamic acid (symbol Glu or E; the ionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins.It is non-essential in humans, meaning the body can synthesize it. *Please select more than one item to compare This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers. Chen, H.; Liu, C.; Chen, D.; Madrid, K.; Peng, S.; Dong, X.; Zhang, M.; Gu, Y. Bacteria-Targeting Conjugates Based on Antimicrobial Peptide for Bacteria Diagnosis and Therapy. Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, FCM and Articles Regulation, Annex I - Authorised Substances, Previous consultations on ECHA’s Executive Director Requests to the Committees, Applications for authorisation consultations, Harmonised classification and labelling consultations, ECHA Executive Director’s requests related to the CLH process, Consultation on potential candidates for substitution, Consultation on derogation to the exclusion criteria, ECHA's Executive Director Requests to the Committees, Consultation on a draft recommendation for amendment of Authorisation List entries, Consultations in the authorisation process, Occupational exposure limits - Call for comments and evidence, Occupational exposure limits - Previous calls for comments and evidence, Occupational exposure limits – Consultations on OEL recommendation, Derogations for the protection of cultural heritage, ECHA's current activities on restrictions, ECHA's completed activities on restriction, Information on Candidate List substances in articles table, Information from the Existing Substances Regulation (ESR), PBT/vPvB assessments under the previous EU chemicals legislation, Adopted opinions and previous consultations on applications for authorisation, Adopted opinions on restriction proposals, Mapping exercise – Plastic additives initiative, Occupational exposure limits substance evaluations, List of substances subject to POPs Regulation, Small and Medium-sized Enterprises (SMEs), Practical examples of chemical safety reports.

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