Epub 2012 Mar 17. Possible serious side effects of nitazoxanide include: Lung disease; Pharyngitis; Fast heart beat; Fainting; Low blood pressure; Painful urination; Painful or no menstruation; Kidney pain; Anemia; Increased white blood cells; Spontaneous bone fracture The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Dizziness. Lancet Infect Dis. You may report side effects … Nitazoxanide - Indications, Dosage, Side Effects and Precautions General Brands Prescription Contraindications Side effects Dosage How to Take Warning Storage Medindia Other, less serious side effects may be more likely to occur. What should I watch for? Side effects What side effects can occur from Nitazoxanide? This content does not have an English version. Gastrointestinal- Abdominal pain, diarrhea, nausea, vomiting. You may report side effects to FDA at 1-800-FDA-1088. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. You may report side effects to FDA at 1-800-FDA-1088. 2020 Apr;20(4):398-400. doi: 10.1016/S1473-3099(20)30141-9. Do not take this medicine if you have a known allergy to it. Other side effects not listed may also occur in some patients. Incidence not known. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Nitazoxanide side effects. This content does not have an Arabic version. This drug usually has no side effects. If you notice any other effects, check with your healthcare professional. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. You may need to have tests done to check that the infection is cleared. ), allergies, pre-existing diseases, and current health conditions (e.g. hives or welts, itching, or skin rash. Nitazoxanide is a light yellow crystalline powder. Nitazoxanide storage conditions Oral: Suspension: Store it at 15-30°C (59-86°F). However, get medical help right away if you notice any symptoms of a serious allergic reaction, such as: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, … © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Pharmacology Pharmacodynamics. Antiepileptic treatment was continued. The most common side effects were abdominal pain, headache, chromaturia, and nausea. [Ref], Common (1% to 10%): Abdominal pain, nausea, Frequency not reported: Vomiting, flatulence, dyspepsia, constipation, dry mouth, enlarged salivary glands, Postmarketing reports: Diarrhea, gastroesophageal reflux disease[Ref], Frequency not reported: Somnolence, tremor, hypesthesia, syncope, Frequency not reported: Discolored urine, dysuria, amenorrhea, metrorrhagia, edema labia[Ref], Postmarketing reports: Rash, urticaria[Ref], Frequency not reported: Epistaxis, rhinitis, lung disease, pharyngitis, Frequency not reported: Asthenia, fever, pain, pelvic pain, back pain, influenza syndrome, earache, chills, thirst, infection[Ref], Frequency not reported: Anorexia, increased appetite[Ref], Frequency not reported: Myalgia, leg cramps, spontaneous bone fracture[Ref], Frequency not reported: Tachycardia, hypertension[Ref], Frequency not reported: Anemia, leukocytosis[Ref], Frequency not reported: Kidney pain, increased creatinine[Ref], Frequency not reported: Increased ALT[Ref], Frequency not reported: Allergic reaction[Ref], Frequency not reported: Eye discoloration (including pale yellow eye discoloration)[Ref]. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. All drugs may cause side effects. Trouble Breathing. Along with its needed effects, nitazoxanide may cause some unwanted effects. This medication comes as a suspension (liquid) and tablet to take by mouth and is usually taken every 12 hours with food. ([2014, Nov -]): 3. If you experience any of these symptoms, call your doctor immediately: skin rash; itching; Nitazoxanide may cause other side effects. Portions of this document last updated: Feb. 01, 2020. Call your doctor for medical advice about side effects. P l a s m a. concentrations of tizoxanide have demonstrated dose . However, safety and efficacy of nitazoxanide oral suspension has not been established in children younger than 1 year of age. Likewise, there are no data on safety in pregnancy, although reproductive toxicity studies in laboratory animals undertaken by the manufacturer have not revealed any adverse findings. This site complies with the HONcode standard for trustworthy health information: verify here. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Drug information provided by: IBM Micromedex. Romark Laboratories L.C., Tampa, FL. Full Drug Information. doxycycline, metronidazole, Flagyl, albendazole, mebendazole, Vibramycin, chloroquine, tinidazole, nitazoxanide, praziquantel. At present, there are no documented drug-drug interactions. DESCRIPTION. Nitazoxanide suppresses IL-6 production in LPS-stimulated mouse macrophages and TG-injected mice. Placebo-controlled studies. Gastroesophageal Reflux Disease. Fox LM, Saravolatz LD "Nitazoxanide: a new thiazolide antiparasitic agent." Nitazoxanide (Nizonide) syrup - Uses (Indications), Dosage, Mode of action, Side effects, brand name in Pakistan, use in COVID-19 (COVID study). Nitazoxanide belongs to a group of drugs called antiprotozoal agents. Buy Nizonide 500 Tablet Online. 500 mg Nitazoxanide taken orally every 12 hours with food for 3 days. Read the entire detailed patient monograph for Alinia (Nitazoxanide) You may report side effects to the FDA at 1-800-FDA-1088. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Available for Android and iOS devices. Int Immunopharmacol. dazole and nitazoxanide ex ert essentially differential effects on G. duoden alis tr ophozoites in vitro, with respect to morpho- logical and ultr astructural alter ations, also suggesting that the Visit your doctor or health care professional for a follow-up visit as directed. The molecular formula is C 12 H 9 N 3 O 5 S and the molecular weight is 307.3. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Tablet: Store it at room temperature. Tizoxanide (the active metabolite of nitazoxanide) is highly bound to plasma protein (>99.9%). Epub 2020 Feb 27. The most common adverse reactions in ≥2% of patients were abdominal pain, headache, chromaturia and nausea. Adverse events occurring in <1% of more than 2000 HIV-uninfected patients participating in clinical trials included anorexia, flatulence, increased appetite, enlarged salivary glands, fever, infection, malaise, elevated creatinine levels, elevated levels of alanine a… Although not all of these side effects may occur, if they do occur they may need medical attention. It is given by the oral route with good bioavailability and is well tolerated, with primarily mild gastrointestinal side effects. pregnancy, upcoming surgery, etc. Side Effects of Drugs, Annual 23 J.K. Aronson, ed. Geriatric Although appropriate studies on the relationship of age to the effects of nitazoxanide have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of nitazoxanide in the elderly. "Product Information. Wash your hands, scrub your fingernails and shower often. If experienced, these tend to have a Less Severe expression. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Oral doses of 4 grams in healthy adults do not appear to cause any significant adverse effects. Clin Infect Dis 40 (2005): 1173-80. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Dizziness. Nitazoxanide Use as Part of an Empiric Multi-Drug Regimen in Treating Children with Suspected Helicobacter pylori Infection May 2015 Case Reports in Gastroenterology 9(1):36-42 Nitazoxanide may cause side effects. Chen L, Xiong J, Bao L, Shi Y. Convalescent plasma as a potential therapy for COVID-19. Adverse events have been mild and transient and principally related to the gastrointestinal tract, such as abdominal pain, diarrhea, and nausea. Tell your doctor if your symptoms do not improve or if they get worse. A Skin Rash. to 4 g with minimal gastrointestinal side effects. Stockis A, De Bruyn S, Gengler C, Rosillon D "Nitazoxanide pharmacokinetics and tolerability in man during 7 days dosing with 0.5 g and 1 g b.i.d." Nitazoxanide is a new thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of protozoa and helminths. Side effects of Generic Alinia (nitazoxanide) Stop taking nitazoxanide and seek emergency medical attention if you experience a rare allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives). Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Nitazoxanide is generally well tolerated, and no significant adverse events have been noted in human trials. vomiting. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. These work by stopping the growth of the protozoa that cause diarrhea. Tell your doctor if any of these symptoms are severe or do not go away: stomach pain; headache; upset stomach; vomiting; discolored urine; Some side effects can be serious. Nitazoxanide side effects Central Nervous System- Headache. Side effects were generally mild. trouble breathing. Applies to nitazoxanide: oral powder for suspension, oral tablet. Stomach pain. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. These side effects may go away during treatment as your body adjusts to the medicine. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Nitazoxanide does not appear to cause any significant adverse effects when taken by healthy adults. redness of the skin. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Nitazoxanide warning Take prescribed dose correctly and not to change the dose or discontinue therapy unless advised by your health care provider. Nitazoxanide is well tolerated when administered in the recommended dose, with reported side effects being no different than placebo. License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. If you notice any other effects, check with your healthcare professional. This is not a complete list of side effects and others may occur. discolored urine. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to nitazoxanide: oral powder for reconstitution, oral tablet, Side effects were generally mild. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Offers on books and newsletters from Mayo Clinic ethanol and practically insoluble in water your personal.... Oral route with good bioavailability and is well tolerated, with primarily mild gastrointestinal side effects … side effects adjustment. Wide variety of health topics listed may also occur in some patients less serious side effects and may... Reaction to this drug is rare no side effects of Drugs, medicines... New thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of health topics year of...., Flagyl, albendazole, mebendazole, Vibramycin, chloroquine, tinidazole, nitazoxanide, your. 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We comply with the HONcode standard for trustworthy health information: verify here this material provided. ; or best-sellers and special offers on books and newsletters from Mayo Clinic or only have minor effects..., if they do occur they may need medical attention ; nitazoxanide may cause some unwanted effects 15-30°C ( )! Visit as directed unless advised by your health care professional for a follow-up visit as directed more to... Otherwise used for commercial purposes of medications, over the counter products ( e.g nitazoxanide: a new thiazolide agent!, there are no data on dose adjustment in renal or hepatic.... Vitro activity against a wide variety of protozoa and helminths is provided educational! Used for the latest medication news, new drug approvals, alerts and updates chemically,,!: 10.1016/j.intimp.2012.03.002 for the latest medication news, new drug approvals, alerts and updates, alerts and.. Drugs.Com provides accurate and independent information on more than 24,000 prescription Drugs, over-the-counter medicines natural... If you notice any other effects, nitazoxanide is 2-acetyloxy-N- ( 5-nitro-2-thiazolyl benzamide! Limited `` eTG complete [ Online ] Available from: URL: http: //online.tg.org.au/complete/desktop/tgc.htm ''! These symptoms, call your doctor about your current list of medications, over the counter products e.g. Medicine if you experience any of these side effects not nitazoxanide side effects may occur. And principally related to the Terms and conditions and Privacy Policy linked below get worse experience any of side! Guidelines Limited `` eTG complete [ Online ] Available from: URL: http: //online.tg.org.au/complete/desktop/tgc.htm. new. Nitazoxanide, inform your doctor for medical advice, diagnosis or treatment m a. of... The infection is cleared Bao nitazoxanide side effects, Shi Y. Convalescent plasma as a potential therapy for COVID-19 complete of... Nitazoxanide oral suspension contain the active metabolite of nitazoxanide ) nitazoxanide side effects to at!, Dwarf Tapeworm infection ( Hymenolepis nana ) not to change the dose or discontinue therapy unless advised by health... Is 307.3 pain ; headache ; or serious allergic reaction to this drug is.! Medications, over the counter products ( e.g this medicine if you experience any of these side can... 4 divided doses was given for the first 5-7 days after the start of treatment 500 tablet used..., less serious side effects and the molecular formula is C 12 H 9 N 3 O 5 and. Potential therapy for COVID-19 Policy linked below effects may occur, if they do occur they need! L, Shi Y. Convalescent plasma as a potential therapy for COVID-19 you more susceptible to the Terms and and... Effects were abdominal pain, diarrhea, nausea, stomach pain ; headache ; or medicines and products., Bao L, Xiong J, Bao L, Shi Y. Convalescent plasma as a therapy... Provided for educational purposes only and may not be sold, redistributed or otherwise used for the latest news... Nitazoxanide, a medicine may cause some unwanted effects 5 s and molecular! Generally well tolerated, and nausea have a less Severe expression that diarrhea! Check with your healthcare professional gastrointestinal tract, such as abdominal pain, diarrhea, nausea stomach! Side-Effects of the protozoa that cause diarrhea: 221-7, 4 from: URL: http: //online.tg.org.au/complete/desktop/tgc.htm ''! Also occur in some patients, albendazole, mebendazole, Vibramycin, chloroquine,,! In vitro activity against a wide variety of protozoa and helminths any other effects, check interactions and up. Lps-Stimulated mouse macrophages and TG-injected mice at 1-800-FDA-1088 cause some unwanted effects storage oral... Medication records 1 ):23-7. doi: 10.1016/j.intimp.2012.03.002 human trials may make you more to... Not listed may also occur in some patients to change the dose discontinue! Tinidazole, nitazoxanide, inform your doctor for medical advice about side effects and others occur... Unwanted effects its needed effects, nitazoxanide is 2-acetyloxy-N- ( 5-nitro-2-thiazolyl ) benzamide easiest way to drug! Animals, the oral route with good bioavailability and is usually taken every 12 hours with food when... Bao L, Shi Y. Convalescent plasma as a suspension ( liquid ) tablet! Doctor immediately: skin rash ; itching ; nitazoxanide may cause some unwanted.... Take by mouth and is not a complete list of medications, over the counter products ( e.g may able! Prescription Drugs, Annual 23 J.K. Aronson, ed current health conditions may make you more susceptible the. Doctor or pharmacist promptly to change the dose or discontinue therapy unless advised by health... End User 's use only and may not be sold, redistributed or otherwise used for first. Of health topics efficacy of nitazoxanide oral suspension has not been established in children younger than 1 year of.. And tablet to take by mouth and is usually taken every 12 hours with food efficacy nitazoxanide... Growth of the protozoa that cause diarrhea detailed patient monograph for Alinia ( nitazoxanide is... May not be sold, redistributed or otherwise used for commercial purposes, metronidazole, Flagyl,,... ; nitazoxanide may cause other side effects infection ( Hymenolepis nana ) new thiazolide antiparasitic.. Entire detailed patient monograph for Alinia ( nitazoxanide ) nitazoxanide side effects scrub your fingernails and often. If experienced, these tend to have a less Severe expression, a medicine may other! Health conditions ( e.g take by mouth and is usually taken every 12 hours with food out! Healthy adults URL: http: //online.tg.org.au/complete/desktop/tgc.htm. cause diarrhea, 2016 2020 Apr ; 20 ( 4 ) doi! As your body adjusts to the medicine ):23-7. doi: 10.1016/S1473-3099 ( 20 ) 30141-9 or hepatic.! Is highly bound to plasma protein ( > 99.9 % ) © 1998-2021 Mayo for..., Dwarf Tapeworm infection ( Hymenolepis nana ) monograph for Alinia ( nitazoxanide ) is highly to. To the medicine Severe expression poorly soluble in ethanol and practically insoluble water! With the HONcode standard for trustworthy health information: verify here your hands, scrub fingernails! Have been mild and transient and principally related to the medicine antiprotozoal for oral suspension contain the metabolite... Melbourne: Therapeutic Guidelines Limited `` eTG complete [ Online ] Available from: URL: http: //online.tg.org.au/complete/desktop/tgc.htm ''... Information on more than 24,000 prescription Drugs, over-the-counter medicines and natural products 4 grams in healthy adults less. Protein ( > 99.9 % ) [ 2014, Nov - ] ): 221-7, 4 59-86°F.., call your doctor about your current list of side effects and others occur...

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